INGREDIENTS LIBRARY

A PRACTICAL OVERVIEW OF THE ACTIVE INGREDIENTS WE USE.

Allantoin

Allantoin is a non-irritating active ingredient that is traditionally extracted from the medicinal plant comfrey. Today, the active ingredient is mainly reproduced in the laboratory for cosmetic purposes, which reduces the risk of allergic reactions.

Why we choose it? An exceptional moisturising, soothing, cell-renewing and anti-irritant ingredient.
What it does? Soothes and protects dry, irritated skin. Supports wound healing and stimulates the growth of new tissue.

Aloe Vera

Aloe Vera is a true miracle cure for the skin because it is full of vitamins, especially A, B, C and E, and has more than 160 proven vital substances such as amino acids, fatty acids, enzymes and minerals that have a cleansing, immune-boosting and regenerating effect on the body and skin.

Aloe Vera is the perfect plant to nourish and soothe sun-stressed, irritated and dry skin. The many antioxidants, enzymes and vitamins A and C it contains have a strong anti-inflammatory effect, making it perfect for relieving acne, burns, irritations, rosacea and eczema.

Scientific studies

Iranian Journal of Medical Sciences (2019) "The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review"

Plant Foods for Human Nutrition (2019) "Aloe vera(L.) Webb.: Natural Sources of Antioxidants – A Review"

Ceramides

Ceramides are the main component of our uppermost layer of skin (the stratum corneum) and form a protective layer that protects the skin from moisture loss and external irritants. As we age and are damaged by the sun, the effectiveness of the natural ceramides in our skin decreases. The consequences are drier and rougher skin and signs of irritation and redness. By adding ceramides, the skin barrier can be repaired and the skin protected from irritation. Since ceramides help to relieve irritation and redness of the skin, they are an indispensable Active ingredient for dry and irritated skin conditions.

Scientific studies

Annual review of physiology (2021) "Ceramides in Metabolism: Key Lipotoxic Players"

Biophysical Journal (2018) "Structural Transitions in Ceramide Cubic Phases during Formation of the Human Skin Barrier"

EGF

Epidermal growth factor (EGF) is a single-chain, non-glycosylated protein found in the fibroblast cells. It is naturally present in the skin cell. In skin care, EGF has a positive effect on skin growth. It increases collagen production and stimulates cell renewal by inducing the healing process in healthy cells. As a result, it works against visible signs of skin aging. It may protect against skin lesions in atopic dermatitis by regulating the skin barrier function.

Scientific studies

Scientific Reports (2018) "Topical administration of EGF suppresses immune response and protects skin barrier in DNCB-induced atopic dermatitis in NC/Nga mice"

Green tea

Green tea is an antioxidant that is extracted from the leaves and buds of the tea plant Camellia sinensis. Green tea mainly contains the antioxidants catechin and polyphenol. These help to neutralize free radicals and reduce signs of skin aging. Green tea also has a calming and anti-inflammatory effect on the skin. It also has a pore-refining effect due to the tannins it contains.

Scientific studies

Critical Reviews in Food Science and Nutrition (2017) "Molecular mechanisms of green tea polyphenols with protective effects against skin photoaging"

Nutrients (2019) "A Review of the Role of Green Tea ( Camellia sinensis ) in Antiphotoaging, Stress Resistance, Neuroprotection, and Autophagy"

Ginseng

Ginseng is one of the oldest natural remedies in the world and an effective anti-aging agent against wrinkles. Thanks to the intensive moisturizing effect of ginseng, the elasticity of the skin increases significantly. Dry skin is gradually plumped up and tightened. This way, a pale complexion or fine Lines are reduced and the skin regains its healthy glow.

This special natural extract stimulates general skin functions and cell renewal by improving blood circulation in the skin. Ginseng therefore ensures that the skin cells are better supplied with important vital substances and has a skin-regenerating effect.

Ginseng also makes your skin lighter. It has the ability to protect the skin from UVB rays and thus reduce photodamage.

Scientific studies

Current Pharmaceutical Design (2017) "Ginseng in Dermatology: A Review"

Journal of Ginseng Research (2021)"The regulatory role of Korean ginseng in skin cells"

Glycerin

Glycerin is an ingredient that is hygroscopic (or a humectant). This means that it can absorb moisture or water from the environment and helps to retain this moisture in the skin. It is absorbed by the skin and mimics the skin's natural moisturizing factor (NMF). Glycerin has the property of helping the skin to regenerate and repair itself. Another property of glycerin is to protect the skin from environmental irritation. When combined with an occlusive agent, glycerin helps to lock moisture into the skin and helps to keep the skin soft and supple.

Scientific studies

The journal of investigative dermatology (2017) "Epidermal Dysfunction Leads to an Age-Associated Increase in Levels of Serum Inflammatory Cytokines"

The Cochrane database systematic reviews (2017) "Emollients and moisturizers for eczema"

Hyaluronic acid

Hyaluronic acid is hydrophilic and therefore has the ability to draw moisture or water from the environment and hold it. It is naturally present in the connective tissue of the skin. With advancing age, the body's own production of hyaluronic acid decreases and can be replaced via topical skin care. absorbed. Different sizes (short, medium and long chain) of hyaluronic acid can be used in skin care. Depending on the length of the hyaluronic acid chain, the active ingredient penetrates to different depths. The lower the chain, the deeper the active ingredient penetrates.

Long-chain hyaluronic acid cannot penetrate the skin barrier and forms a film on the skin. This improves the elasticity and moisture content of the skin. This hyaluronic acid is also nourishing and soothing due to its anti-inflammatory properties. Medium-chain hyaluronic acid is absorbed into the skin and ensures plump and firm skin by storing moisture in the skin's connective tissue. Short-chain hyaluronic acid is the smallest hyaluronic acid and therefore penetrates deeper into the skin than hyaluronic acids of other sizes.

Scientific studies

International Journal of Molecular Sciences (2019) "Role of HYBID (Hyaluronan Binding Protein Involved in Hyaluronan Depolymerization), Alias ​​KIAA1199/CEMIP, in Hyaluronan Degradation in Normal and Photoaged Skin"

International Journal of Biological Macromolecules (2018) "Hyaluronic acid, a promising skin rejuvenating biomedicine: A review of recent updates and pre-clinical and clinical investigations on cosmetic and nutricosmetic effects"

Chamomile

Chamomile is extracted from the chamomile flower and contains, among other things, alpha-bisabolol, blue chamazulene, farnesene and polyenes. These provide the anti-inflammatory, antibacterial and antipruritic properties of chamomile. By using chamomile in skin care, skin irritations can be reduced and skin regeneration can be accelerated. This makes chamomile suitable for sensitive and dry skin.

Scientific studies

Essential Psychiatry for the Aesthetic Practitioner (2021) "An Approach to Cosmeceuticals"

Journal of the American Academy of Dermatology (2019) "Management of acute radiation dermatitis: A review of the literature and proposal for treatment algorithm"

Lactic acid

Lactic acid is one of the alpha hydroxy acids (AHA), which act on the surface of the skin and are water-soluble. Lactic acid can therefore gently dissolve dead skin cells on the surface of the skin and moisturize the skin. This allows the active ingredients to be more easily absorbed by the skin and improves the overall appearance of the skin. Lactic acid can also work against excessive keratinization and refines pores.

Scientific studies

Current Pharmaceutical Biotechnology (2020) "Lactic Acid Bacteria and Lactic Acid for Skin Health and Melanogenesis Inhibition"

Skin Research & Technology (2020) "Convenience biosensing approach of lactic acid in stratum corneum for skin care assessment"

Moss extracts

Moss extract (MossCellTech) is an active ingredient that has the property of inhibiting the breakdown of collagen. It also helps to reduce pigment spots and thus has a positive effect on the skin's appearance.

Scientific studies

Plants (2021) "Collagenase and Tyrosinase Inhibitory Effect of Isolated Constituents from the MossPolytrichum formosum"

Panthenol (provitamin B5)

Panthenol is also called provitamin B5 or dexpanthenol. It is a provitamin - a precursor or substance that the body can convert into a certain vitamin - B5. Panthenol has the property of binding moisture. Panthenol draws water into the cells and keeps it in the tissue, providing a feeling of well-being and an improved complexion. This increases the moisture level and elasticity of the skin. It increases the skin's moisture and supports our skin barrier. It has an anti-inflammatory effect over a longer period of time and relieves irritated, tight and dry skin. It is very suitable for irritated skin conditions. The healing effect has been clinically proven. This is why panthenol is often a component of wound ointments.

Scientific studies

Phytotherapy Research (2019) "The potential role of B5: A stitch in time and switch in cytokine"

Advances in Skin & Wound Care (2018) "Effects of Vitamin B Complex and Vitamin C on Human Skin Cells: Is the Perceived Effect Measurable?"

Platinum Peptide

Peptides in general are components of proteins and are themselves made up of amino acids. Proteins and therefore peptides are naturally found in the skin. They give the skin its elasticity and firmness. In skin care, peptides can therefore improve the complexion and refresh the skin. Some peptides can, for example, have a soothing effect on the skin.

Platinum peptides contain an anti-wrinkle ingredient that improves collagen formation and skin elasticity. This leads to a reduction in fine lines and wrinkles on the skin. The active ingredient is bound to the surface of a platinum particle, which promotes the solubility and stabilization of the active ingredient. This binding makes the active ingredient more effective than free peptides.

Scientific studies

Skin Research and Technology (2018) "Antimicrobial peptides activity in the skin"

Peptides (2019) "Potential role of natural bioactive peptides for development of cosmeceutical skin products"

Red algae (astaxanthin)

Astaxanthin is one of the most powerful antioxidants. It protects collagen from damage caused by free radicals and inhibits collagen-degrading enzymes. Astaxanthin stimulates collagen synthesis and ensures a smooth complexion and firm skin in the long term.

Scientific studies

Nutrients (2018) "Astaxanthin in Skin Health, Repair, and Disease: A Comprehensive Review"

Journal of Cosmetic Dermatology (2019) "Protective effects of astaxanthin on skin: Recent scientific evidence, possible mechanisms, and potential indications"

Protox complex

Protox complex consists of olive leaf extracts, jujube extracts and levan. The combination of these active ingredients makes our protox complex rich in antioxidants and has a very moisturizing effect. The jujube is rich in antioxidants and vitamin C and helps the body to protect itself from harmful free radicals and prevents the formation of oxidized proteins. The olive leaf extracts contained in the protox complex protect the skin with additional antioxidants and moisturize the skin. The extract activates the proteasome, which allows oxidized proteins to be broken down more effectively. The levan has an anti-inflammatory effect and a moisturizing effect like hyaluronic acid.

Scientific studies

Biomaterials Science (2018) "An injectable and physical levan-based hydrogel as a dermal filler for soft tissue augmentation"

American Journal of Clinical Dermatology (2018) "Natural Oils for Skin-Barrier Repair: Ancient Compounds Now Backed by Modern Science"

Tetrapeptides

Tetrapeptides are peptides that have a soothing, moisturizing, firming and smoothing effect on the skin. It can reduce swelling under the eyes due to its soothing properties. The peptide prevents glycation, which has an anti-aging effect and makes the skin look elasticity and moisture are preserved.

Scientific studies

Journal of cosmetic dermatology (2011) "Facial skin-lightening benefits of the tetrapeptide Pro-Lys-Glu-Lys on subjects with skin types V-VI living in South Africa"

International journal of molecular sciences (2019) "Anti-Wrinkle Benefits of Peptides Complex Stimulating Skin Basement Membrane Proteins Expression"

Vitamin B3: Niacinamide

Niacinamide is the water-soluble amide form of vitamin B3. It cannot be produced by the body itself, but must be absorbed through food (such as fish or meat) or via topical skin care. It helps to build the skin's protective barrier and thus prevents moisture loss. This makes niacinamide well suited for dry skin conditions. It also plays an important role in the metabolic processes of skin cells and promotes skin renewal. It creates an even skin appearance by smoothing the skin and minimizing enlarged pores.

Scientific studies

Advances in Skin & Wound Care (2018) "Effects of Vitamin B Complex and Vitamin C on Human Skin Cells: Is the Perceived Effect Measurable?"

Clinical and Experimental Dermatology (2017) "Use of nicotinamide in dermatology"

Vitamin C

Vitamin C is an antioxidant molecule that penetrates the skin extremely well. It can improve the complexion by lightening uneven skin tone by preventing oxidation caused by free radicals. Vitamin C also promotes collagen synthesis (collagen formation) and has a regenerating and soothing effect on the skin. It also helps to reduce pigment spots because vitamin C inhibits melanogenesis (formation of melanin). It accelerates wound healing, stimulates cell renewal and prevents radiation-related damage.

Scientific studies

Scientific reports (2020) "Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin"

Scientific reports (2018) "Protective effect of pre- and post-vitamin C treatments on UVB-irradiation-induced skin damage"

Vitamin E

Vitamin E, also known as tocopherol, is an antioxidant and protects the skin from free radicals. Its lipid-soluble properties support the skin's tocopherol levels. This allows it to penetrate into the deepest layers of the stratum corneum and protect it from oxidative stress. Vitamin E also protects E against photoaging, as it can reduce hyperpigmentation caused by ultraviolet light. It has cell-renewing and anti-inflammatory properties and helps to make the skin feel relaxed.

Scientific studies

Journal of Cosmetic Dermatology Wiley (2020) "Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial"

Molecular Aspects of Medicine (2007) "Vitamin E in human skin: Organ-specific physiology and considerations for its use in dermatology"

Zinc

Zinc is an active ingredient that has antimicrobial and sebum-regulating effects. This prevents pores from becoming clogged, as zinc can regulate the amount of natural skin oils. It can also reduce inflammation and inhibit the growth of Probionibacterium acnes, which means zinc can help fight acne.

Scientific studies

Nutrients (2018) "Zinc and Skin Disorders"

Nutrients (2018) "The Role of the Slc39a Family of Zinc Transporters in Zinc Homeostasis in Skin"